Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer ther...
Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
T cells generated from human iPSCs engineered to express a chimeric antigen receptor display innate lymphoid properties and inhibit tumor growth in mice.
Progress in adoptive T-cell therapy for cancer and infectious diseases
1
,
2
is hampered by the lack of readily available, antigen-specific, human T lymphocytes. Pluripotent stem ce...
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Full title
Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5722218
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5722218
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.2678