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Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer ther...

Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer ther...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5722218

Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy

About this item

Full title

Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2013-10, Vol.31 (10), p.928-933

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

T cells generated from human iPSCs engineered to express a chimeric antigen receptor display innate lymphoid properties and inhibit tumor growth in mice.
Progress in adoptive T-cell therapy for cancer and infectious diseases
1
,
2
is hampered by the lack of readily available, antigen-specific, human T lymphocytes. Pluripotent stem ce...

Alternative Titles

Full title

Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5722218

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5722218

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.2678

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