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AMPK: a nutrient and energy sensor that maintains energy homeostasis

AMPK: a nutrient and energy sensor that maintains energy homeostasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5726489

AMPK: a nutrient and energy sensor that maintains energy homeostasis

About this item

Full title

AMPK: a nutrient and energy sensor that maintains energy homeostasis

Publisher

London: Nature Publishing Group UK

Journal title

Nature reviews. Molecular cell biology, 2012-04, Vol.13 (4), p.251-262

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Key Points
AMP-activated protein kinase (AMPK) occurs as heterotrimeric protein complexes that monitor cellular energy status by sensing the concentrations of ATP, ADP and AMP.
Displacement of ATP by ADP or AMP at one site on the AMPK γ-subunit promotes the net phosphorylation of a conserved Thr residue within the activation loop of the kinas...

Alternative Titles

Full title

AMPK: a nutrient and energy sensor that maintains energy homeostasis

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5726489

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5726489

Other Identifiers

ISSN

1471-0072

E-ISSN

1471-0080

DOI

10.1038/nrm3311

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