Social stress induces neurovascular pathology promoting depression
Social stress induces neurovascular pathology promoting depression
About this item
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Author / Creator
Menard, Caroline , Pfau, Madeline L. , Hodes, Georgia E. , Kana, Veronika , Wang, Victoria X. , Bouchard, Sylvain , Takahashi, Aki , Flanigan, Meghan E. , Aleyasin, Hossein , LeClair, Katherine B. , Janssen, William G. , Labonté, Benoit , Parise, Eric M. , Lorsch, Zachary S. , Golden, Sam A. , Heshmati, Mitra , Tamminga, Carol , Turecki, Gustavo , Campbell, Matthew , Fayad, Zahi A. , Tang, Cheuk Ying , Merad, Miriam and Russo, Scott J.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Studies suggest that heightened peripheral inflammation contributes to the pathogenesis of major depressive disorder. We investigated the effect of chronic social defeat stress, a mouse model of depression, on blood–brain barrier (BBB) permeability and infiltration of peripheral immune signals. We found reduced expression of the endothelial cell ti...
Alternative Titles
Full title
Social stress induces neurovascular pathology promoting depression
Authors, Artists and Contributors
Author / Creator
Pfau, Madeline L.
Hodes, Georgia E.
Kana, Veronika
Wang, Victoria X.
Bouchard, Sylvain
Takahashi, Aki
Flanigan, Meghan E.
Aleyasin, Hossein
LeClair, Katherine B.
Janssen, William G.
Labonté, Benoit
Parise, Eric M.
Lorsch, Zachary S.
Golden, Sam A.
Heshmati, Mitra
Tamminga, Carol
Turecki, Gustavo
Campbell, Matthew
Fayad, Zahi A.
Tang, Cheuk Ying
Merad, Miriam
Russo, Scott J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5726568
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5726568
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-017-0010-3
