RNA polymerase III limits longevity downstream of TORC1
RNA polymerase III limits longevity downstream of TORC1
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Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
RNA polymerase III is a key evolutionarily conserved regulator of longevity that may have potential as a therapeutic target for age-related conditions.
Pol III inhibition extends lifespan
Inhibition of target of rapamycin kinase complex 1 (TORC1) by rapamycin promotes longevity across the animal kingdom. TORC1 tightly regulates the activity o...
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Full title
RNA polymerase III limits longevity downstream of TORC1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5732570
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5732570
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature25007
