The complex genetics of hypoplastic left heart syndrome
The complex genetics of hypoplastic left heart syndrome
About this item
Full title
Author / Creator
Liu, Xiaoqin , Yagi, Hisato , Saeed, Shazina , Bais, Abha S , Gabriel, George C , Chen, Zhaohan , Peterson, Kevin A , Li, You , Schwartz, Molly C , Reynolds, William T , Saydmohammed, Manush , Gibbs, Brian , Wu, Yijen , Devine, William , Chatterjee, Bishwanath , Klena, Nikolai T , Kostka, Dennis , de Mesy Bentley, Karen L , Ganapathiraju, Madhavi K , Dexheimer, Phillip , Leatherbury, Linda , Khalifa, Omar , Bhagat, Anchit , Zahid, Maliha , Pu, William , Watkins, Simon , Grossfeld, Paul , Murray, Stephen A , Porter, George A , Tsang, Michael , Martin, Lisa J , Benson, D Woodrow , Aronow, Bruce J and Lo, Cecilia W
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Cecilia Lo and colleagues report the recovery of mice with hypoplastic left heart syndrome (HLHS) from a large mutagenesis screen. They find genetic heterogeneity among HLHS mice and functionally validate mutations in two genes,
Sap130
and
Pcdha
, as contributing to HLHS in a combinatorial manner.
Congenital heart disease (CHD) affec...
Alternative Titles
Full title
The complex genetics of hypoplastic left heart syndrome
Authors, Artists and Contributors
Author / Creator
Yagi, Hisato
Saeed, Shazina
Bais, Abha S
Gabriel, George C
Chen, Zhaohan
Peterson, Kevin A
Li, You
Schwartz, Molly C
Reynolds, William T
Saydmohammed, Manush
Gibbs, Brian
Wu, Yijen
Devine, William
Chatterjee, Bishwanath
Klena, Nikolai T
Kostka, Dennis
de Mesy Bentley, Karen L
Ganapathiraju, Madhavi K
Dexheimer, Phillip
Leatherbury, Linda
Khalifa, Omar
Bhagat, Anchit
Zahid, Maliha
Pu, William
Watkins, Simon
Grossfeld, Paul
Murray, Stephen A
Porter, George A
Tsang, Michael
Martin, Lisa J
Benson, D Woodrow
Aronow, Bruce J
Lo, Cecilia W
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5737968
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5737968
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3870
