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Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment

Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5738363

Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment

About this item

Full title

Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2017-12, Vol.7 (1), p.17949-13, Article 17949

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

MiR-34a acts as tumor suppressor microRNA (miRNA) in several cancers, including multiple myeloma (MM), by controlling the expression of target proteins involved in cell cycle, differentiation and apoptosis. Here, we have investigated the combination between miR-34a and γ-secretase inhibitor (γSI), Sirtinol or zoledronic acid (ZOL) in order to enhan...

Alternative Titles

Full title

Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5738363

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5738363

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-017-18186-0

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