Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic
Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Reference strains are a key component of laboratory research, providing a common background allowing for comparisons across a community of researchers. However, laboratory passage of these strains has been shown to lead to reduced fitness and the attenuation of virulence in some species. In this study we show the opposite in the fungal pathogen
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Full title
Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5738413
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5738413
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-18106-2
