RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes gr...
RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Keratinocyte (KC) hyper-proliferation and epidermal thickening are characteristic features of psoriasis lesions, but the specific contributions of KCs to plaque formation are not fully understood. This study used RNA-seq to investigate the transcriptome of primary monolayer KC cultures grown from lesional (PP) and non-lesional (PN) biopsies of psor...
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Full title
RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5741737
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5741737
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-18404-9