ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming
ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming
About this item
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Author / Creator
Mishra, Prachi , Tang, Wei , Putluri, Vasanta , Dorsey, Tiffany H , Jin, Feng , Wang, Fang , Zhu, Donewei , Amable, Lauren , Deng, Tao , Zhang, Shaofei , Killian, J Keith , Wang, Yonghong , Minas, Tsion Z , Yfantis, Harry G , Lee, Dong H , Sreekumar, Arun , Bustin, Michael , Liu, Wei , Putluri, Nagireddy and Ambs, Stefan
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
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Publication information
Publisher
United States: American Society for Clinical Investigation
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Scope and Contents
Contents
Metabolic reprogramming in breast tumors is linked to increases in putative oncogenic metabolites that may contribute to malignant transformation. We previously showed that accumulation of the oncometabolite, 2-hydroxyglutarate (2HG), in breast tumors was associated with MYC signaling, but not with isocitrate dehydrogenase (IDH) mutations, suggesti...
Alternative Titles
Full title
ADHFE1 is a breast cancer oncogene and induces metabolic reprogramming
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5749504
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5749504
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI93815
