Log in to save to my catalogue

The microbial metabolite desaminotyrosine protects from influenza through type I interferon

The microbial metabolite desaminotyrosine protects from influenza through type I interferon

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5753406

The microbial metabolite desaminotyrosine protects from influenza through type I interferon

About this item

Full title

The microbial metabolite desaminotyrosine protects from influenza through type I interferon

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2017-08, Vol.357 (6350), p.498-502

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

The microbiota is known to modulate the host response to influenza infection through as-yet-unclear mechanisms. We hypothesized that components of the microbiota exert effects through type I interferon (IFN), a hypothesis supported by analysis of influenza in a gain-of-function genetic mouse model. Here we show that a microbially associated metabol...

Alternative Titles

Full title

The microbial metabolite desaminotyrosine protects from influenza through type I interferon

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5753406

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5753406

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.aam5336

How to access this item