The microbial metabolite desaminotyrosine protects from influenza through type I interferon
The microbial metabolite desaminotyrosine protects from influenza through type I interferon
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Publisher
United States: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
United States: American Association for the Advancement of Science
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Scope and Contents
Contents
The microbiota is known to modulate the host response to influenza infection through as-yet-unclear mechanisms. We hypothesized that components of the microbiota exert effects through type I interferon (IFN), a hypothesis supported by analysis of influenza in a gain-of-function genetic mouse model. Here we show that a microbially associated metabol...
Alternative Titles
Full title
The microbial metabolite desaminotyrosine protects from influenza through type I interferon
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5753406
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5753406
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aam5336