Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Media...
Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge
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Full title
Author / Creator
Morozov, Giora I. , Porat, Nurith , Kushnir, Tatyana , Najmuldeen, Hastyar , Adawi, Asad , Chalifa-Caspi, Vered , Benisty, Rachel , Ohayon, Ariel , Liron, Ofir , Azriel, Shalhevet , Malka, Itai , Dotan, Shahar , Portnoi, Maxim , Piotrowski, Andrew A. , Kafka, Daniel , Hajaj, Barak , Fishilevich, Tali , Shagan, Marilou , Tal, Michael , Ellis, Ron , Morrison, Donald A. , Mitchell, Andrea M. , Mitchell, Timothy J. , Dagan, Ron , Yesilkaya, Hasan and Nebenzahl, Yaffa Mizrachi
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Pneumococcal flavin reductase (FlaR) is known to be cell-wall associated and possess age dependent antigenicity in children. This study aimed at characterizing FlaR and elucidating its involvement in pneumococcal physiology and virulence. Bioinformatic analysis of FlaR sequence identified three-conserved cysteine residues, suggesting a transition m...
Alternative Titles
Full title
Flavin Reductase Contributes to Pneumococcal Virulence by Protecting from Oxidative Stress and Mediating Adhesion and Elicits Protection Against Pneumococcal Challenge
Authors, Artists and Contributors
Author / Creator
Porat, Nurith
Kushnir, Tatyana
Najmuldeen, Hastyar
Adawi, Asad
Chalifa-Caspi, Vered
Benisty, Rachel
Ohayon, Ariel
Liron, Ofir
Azriel, Shalhevet
Malka, Itai
Dotan, Shahar
Portnoi, Maxim
Piotrowski, Andrew A.
Kafka, Daniel
Hajaj, Barak
Fishilevich, Tali
Shagan, Marilou
Tal, Michael
Ellis, Ron
Morrison, Donald A.
Mitchell, Andrea M.
Mitchell, Timothy J.
Dagan, Ron
Yesilkaya, Hasan
Nebenzahl, Yaffa Mizrachi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5762878
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5762878
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-18645-8
