Targeting melanoma stem cells with the Vitamin E derivative δ-tocotrienol
Targeting melanoma stem cells with the Vitamin E derivative δ-tocotrienol
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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The prognosis of metastatic melanoma is very poor, due to the development of drug resistance. Cancer stem cells (CSCs) may play a crucial role in this mechanism, contributing to disease relapse. We first characterized CSCs in melanoma cell lines. We observed that A375 (but not BLM) cells are able to form melanospheres and show CSCs traits: expressi...
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Full title
Targeting melanoma stem cells with the Vitamin E derivative δ-tocotrienol
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5766483
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5766483
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-19057-4
