Characterization of Dopaminergic System in the Striatum of Young Adult Park2−/− Knockout Rats
Characterization of Dopaminergic System in the Striatum of Young Adult Park2−/− Knockout Rats
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Mutations in parkin gene (
Park2
) are linked to early-onset autosomal recessive Parkinson’s disease (PD) and young-onset sporadic PD.
Park2
knockout (PKO) rodents; however, do not display neurodegeneration of the nigrostriatal pathway, suggesting age-dependent compensatory changes. Our goal was to examine dopaminergic (DAergic) system...
Alternative Titles
Full title
Characterization of Dopaminergic System in the Striatum of Young Adult Park2−/− Knockout Rats
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5784013
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5784013
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-017-18526-0
