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The host protecting the tumor from the host — targeting PD‑L1 expressed by host cells

The host protecting the tumor from the host — targeting PD‑L1 expressed by host cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5785247

The host protecting the tumor from the host — targeting PD‑L1 expressed by host cells

About this item

Full title

The host protecting the tumor from the host — targeting PD‑L1 expressed by host cells

Author / Creator

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2018-02, Vol.128 (2), p.570-572

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Tumors frequently escape from immune surveillance by hijacking the natural control mechanisms that regulate normal immune responses. The programmed death-1 receptor (PD‑1) on T cells normally helps limit excessive immune activation, but it can also suppress beneficial antitumor immunity. In the clinic, blocking either PD‑1 or one of its principal c...

Alternative Titles

Full title

The host protecting the tumor from the host — targeting PD‑L1 expressed by host cells

Authors, Artists and Contributors

Author / Creator

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5785247

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5785247

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI99047

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