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mTOR Cross-Talk in Cancer and Potential for Combination Therapy

mTOR Cross-Talk in Cancer and Potential for Combination Therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5789373

mTOR Cross-Talk in Cancer and Potential for Combination Therapy

About this item

Full title

mTOR Cross-Talk in Cancer and Potential for Combination Therapy

Publisher

Switzerland: MDPI AG

Journal title

Cancers, 2018-01, Vol.10 (1), p.23

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

More information

Scope and Contents

Contents

The mammalian Target of Rapamycin (mTOR) pathway plays an essential role in sensing and integrating a variety of exogenous cues to regulate cellular growth and metabolism, in both physiological and pathological conditions. mTOR functions through two functionally and structurally distinct multi-component complexes, mTORC1 and mTORC2, which interact...

Alternative Titles

Full title

mTOR Cross-Talk in Cancer and Potential for Combination Therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5789373

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5789373

Other Identifiers

ISSN

2072-6694

E-ISSN

2072-6694

DOI

10.3390/cancers10010023

How to access this item