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Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5796022

Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

About this item

Full title

Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

Publisher

Switzerland: MDPI AG

Journal title

International journal of molecular sciences, 2017-12, Vol.19 (1), p.72

Language

English

Formats

Publication information

Publisher

Switzerland: MDPI AG

Subjects

More information

Scope and Contents

Contents

Aurora kinases (AKs) are serine/threonine kinases that are essential for cell division. Humans have three AK genes: AKA, AKB, and AKC. AKA is required for centrosome assembly, centrosome separation, and bipolar spindle assembly, and its mutation leads to abnormal spindle morphology. AKB is required for the spindle checkpoint and proper cytokinesis,...

Alternative Titles

Full title

Differential Selective Pressures Experienced by the Aurora Kinase Gene Family

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5796022

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5796022

Other Identifiers

ISSN

1422-0067,1661-6596

E-ISSN

1422-0067

DOI

10.3390/ijms19010072

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