Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tool...
Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Apathy is one of the most prevalent and progressive psychiatric symptoms in Huntington’s disease (HD) patients. However, preclinical work in HD mouse models tends to focus on molecular and motor, rather than affective, phenotypes. Measuring behavior in mice often produces noisy data and requires large cohorts to detect phenotypic rescue with approp...
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Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5797185
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5797185
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-20607-7
