The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction
The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The FGFR4-388Arg variant has been related to poor prognosis in several types of cancer, including lung cancer. The mechanism underlying this association has not been addressed in detail in patients with this pathology. Here, we report that this FGFR4 variant induces MAPK and STAT3 activation and causes pro-oncogenic effects in NSCLC
in vitro
...
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Full title
The FGFR4-388arg Variant Promotes Lung Cancer Progression by N-Cadherin Induction
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5799167
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5799167
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-20570-3
