CCN3 suppresses TGF-β1-induced extracellular matrix accumulation in human mesangial cells in vitro
CCN3 suppresses TGF-β1-induced extracellular matrix accumulation in human mesangial cells in vitro
About this item
Full title
Author / Creator
Liu, Hai-fei , Liu, Hong , Lv, Lin-li , Ma, Kun-ling , Wen, Yi , Chen, Long and Liu, Bi-cheng
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Glomerular sclerosis is characterized by mesangial cell proliferation and progressive extracellular matrix （ECM） accumulation. CCN3 belongs to the CCN family of matrix proteins; increasing evidence suggests that CCN3 is an endogenous negative regulator of the ECM and fibrosis. However, the exact role of CCN3 in the accumulation of ECM remains unkno...
Alternative Titles
Full title
CCN3 suppresses TGF-β1-induced extracellular matrix accumulation in human mesangial cells in vitro
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5800473
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5800473
Other Identifiers
ISSN
1671-4083
E-ISSN
1745-7254
DOI
10.1038/aps.2017.87
