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Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5803371

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

About this item

Full title

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2018-02, Vol.24 (2), p.176-185

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Peter Scacheri and colleagues report that the activity of enhancer elements in metastatic osteosarcoma is distinct from that in primary tumors and plays a functional role in metastatic progression of osteosarcoma.
Metastasis results from a complex set of traits acquired by tumor cells, distinct from those necessary for tumorigenesis. Here, we in...

Alternative Titles

Full title

Positively selected enhancer elements endow osteosarcoma cells with metastatic competence

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5803371

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5803371

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.4475

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