The synergistic role of ATP‐dependent drug efflux pump and focal adhesion signaling pathways in vino...
The synergistic role of ATP‐dependent drug efflux pump and focal adhesion signaling pathways in vinorelbine resistance in lung cancer
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United States: John Wiley & Sons, Inc
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English
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United States: John Wiley & Sons, Inc
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The vinorelbine (VRB) plus cisplatin regimen is widely used to treat non–small cell lung cancer (NSCLC), but its cure rate is poor. Drug resistance is the primary driver of chemotherapeutic failure, and the causes of resistance remain unclear. By focusing on the focal adhesion (FA) pathway, we have highlighted a signaling pathway that promotes VRB...
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The synergistic role of ATP‐dependent drug efflux pump and focal adhesion signaling pathways in vinorelbine resistance in lung cancer
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5806107
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5806107
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ISSN
2045-7634
E-ISSN
2045-7634
DOI
10.1002/cam4.1282