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Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism

Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5824856

Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism

About this item

Full title

Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2018-03, Vol.128 (3), p.1087-1105

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

The skeleton has emerged as an important regulator of systemic glucose homeostasis, with osteocalcin and insulin representing prime mediators of the interplay between bone and energy metabolism. However, genetic evidence indicates that osteoblasts can influence global energy metabolism through additional, as yet unknown, mechanisms. Here, we report...

Alternative Titles

Full title

Vhl deletion in osteoblasts boosts cellular glycolysis and improves global glucose metabolism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5824856

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5824856

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI97794

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