Role of a selecting ligand in shaping the murine γδ-TCR repertoire
Role of a selecting ligand in shaping the murine γδ-TCR repertoire
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
Unlike αβ-T lineage cells, where the role of ligand in intrathymic selection is well established, the role of ligand in the development of γδ-T cells remains controversial. Here we provide evidence for the role of a bona fide selecting ligand in shaping the γδ-T cell-receptor (TCR) repertoire. Reactivity of the γδ-TCR with the major histocompatibil...
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Full title
Role of a selecting ligand in shaping the murine γδ-TCR repertoire
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5828614
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5828614
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1718328115