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Role of a selecting ligand in shaping the murine γδ-TCR repertoire

Role of a selecting ligand in shaping the murine γδ-TCR repertoire

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5828614

Role of a selecting ligand in shaping the murine γδ-TCR repertoire

About this item

Full title

Role of a selecting ligand in shaping the murine γδ-TCR repertoire

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (8), p.1889-1894

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Unlike αβ-T lineage cells, where the role of ligand in intrathymic selection is well established, the role of ligand in the development of γδ-T cells remains controversial. Here we provide evidence for the role of a bona fide selecting ligand in shaping the γδ-T cell-receptor (TCR) repertoire. Reactivity of the γδ-TCR with the major histocompatibil...

Alternative Titles

Full title

Role of a selecting ligand in shaping the murine γδ-TCR repertoire

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5828614

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5828614

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1718328115

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