PKM2 Is Required to Activate Myeloid Dendritic Cells from Patients with Severe Aplastic Anemia
PKM2 Is Required to Activate Myeloid Dendritic Cells from Patients with Severe Aplastic Anemia
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Publisher
Cairo, Egypt: Hindawi Publishing Corporation
Journal title
Language
English
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Publisher
Cairo, Egypt: Hindawi Publishing Corporation
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Scope and Contents
Contents
Severe aplastic anemia (SAA) is an autoimmune disease in which bone marrow failure is mediated by activated myeloid dendritic cells (mDCs) and T lymphocytes. Recent research has identified a strong immunomodulatory effect of pyruvate kinase M2 (PKM2) on dendritic cells in immune-mediated diseases. In this study, we aimed to explore the role of PKM2...
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Full title
PKM2 Is Required to Activate Myeloid Dendritic Cells from Patients with Severe Aplastic Anemia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5832124
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5832124
Other Identifiers
ISSN
1942-0900
E-ISSN
1942-0994
DOI
10.1155/2018/1364165
