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Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain

Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5832877

Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain

About this item

Full title

Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-03, Vol.8 (1), p.1-17, Article 3845

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Voltage-gated sodium channels Na
V
1.7, Na
V
1.8 and Na
V
1.9 have been the focus for pain studies because their mutations are associated with human pain disorders, but the role of Na
V
1.6 in pain is less understood. In this study, we selectively knocked out Na
V
1.6 in dorsal root ganglion (DRG) neurons, using Na
...

Alternative Titles

Full title

Conditional knockout of NaV1.6 in adult mice ameliorates neuropathic pain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5832877

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5832877

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-22216-w

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