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MCL-1 is a prognostic indicator and drug target in breast cancer

MCL-1 is a prognostic indicator and drug target in breast cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5833338

MCL-1 is a prognostic indicator and drug target in breast cancer

About this item

Full title

MCL-1 is a prognostic indicator and drug target in breast cancer

Publisher

London: Nature Publishing Group UK

Journal title

Cell death & disease, 2018-01, Vol.9 (2), p.19-14, Article 19

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Analysis of publicly available genomic and gene expression data demonstrates that
MCL1
expression is frequently elevated in breast cancer. Distinct from other pro-survival Bcl-2 family members, the short half-life of MCL-1 protein led us to investigate MCL-1 protein expression in a breast cancer tissue microarray and correlate this with clini...

Alternative Titles

Full title

MCL-1 is a prognostic indicator and drug target in breast cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5833338

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5833338

Other Identifiers

ISSN

2041-4889

E-ISSN

2041-4889

DOI

10.1038/s41419-017-0035-2

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