Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degene...
Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk
About this item
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Author / Creator
Guo, Wei , Zhang, Bin , Mu, Kun , Feng, Shi-Qing , Dong, Zhan-Yin , Ning, Guang-Zhi , Li, Hao-Ran , Liu, Shen , Zhao, Ling , Li, Yan , Yu, Bing-Bing , Duan, Hui-Quan , Sun, Chao and Li, Yong-Jin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Intervertebral disc degeneration (IDD) is an important factor leading to low back pain, but the underlying mechanisms remain poorly understood. Compared with normal nucleus pulposus (NP) tissues, the expression of circ-GRB10 was downregulated in IDD. Furthermore, overexpression of circ-GRB10 inhibited NP cell apoptosis. circ-GRB10 could sequester m...
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Full title
Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5833826
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5833826
Other Identifiers
ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-017-0232-z
