Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain
Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
DNA methylation is an important epigenetic modification involved in gene regulation and transposable element silencing. Changes in DNA methylation can be heritable and, thus, can lead to the formation of stable epialleles. A well-characterized example of a stable epiallele in plants is fwa, which consists of the loss of DNA cytosine methylation (5m...
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Full title
Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5834696
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5834696
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1716945115