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Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain

Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5834696

Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain

About this item

Full title

Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (9), p.E2125-E2134

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

DNA methylation is an important epigenetic modification involved in gene regulation and transposable element silencing. Changes in DNA methylation can be heritable and, thus, can lead to the formation of stable epialleles. A well-characterized example of a stable epiallele in plants is fwa, which consists of the loss of DNA cytosine methylation (5m...

Alternative Titles

Full title

Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5834696

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5834696

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1716945115

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