Yeast surface display platform for rapid discovery of conformationally selective nanobodies
Yeast surface display platform for rapid discovery of conformationally selective nanobodies
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Author / Creator
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS) , McMahon, Conor , Baier, Alexander S. , Pascolutti, Roberta , Wegrecki, Marcin , Zheng, Sanduo , Ong, Janice X. , Erlandson, Sarah C. , Hilger, Daniel , Rasmussen, Søren G. F. , Ring, Aaron M. , Manglik, Aashish and Kruse, Andrew C.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Camelid single-domain antibody fragments (‘nanobodies’) provide the remarkable specificity of antibodies within a single 15-kDa immunoglobulin V
HH
domain. This unique feature has enabled applications ranging from use as biochemical tools to therapeutic agents. Nanobodies have emerged as especially useful tools in protein structural biology,...
Alternative Titles
Full title
Yeast surface display platform for rapid discovery of conformationally selective nanobodies
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5839991
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5839991
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/s41594-018-0028-6
