KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
About this item
Full title
Author / Creator
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS) , Wang, Yugang , Guo, Yusong R. , Liu, Ke , Yin, Zheng , Liu, Rui , Xia, Yan , Tan, Lin , Yang, Peiying , Lee, Jong-Ho , Li, Xin-jian , Hawke, David , Zheng, Yanhua , Qian, Xu , Lyu, Jianxin , He, Jie , Xing, Dongming , Tao, Yizhi Jane and Lu, Zhimin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The histone acetyl transferase KAT2A (also known as GCN5) can also catalyse histone succinylation, with the α-KGDH complex providing a local source of succinyl-CoA.
GCN5 in histone succyinylation
Succinylation of lysines has been identified as a post-translational modification of histones, but the enzymes that deposit it and its functional co...
Alternative Titles
Full title
KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5841452
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5841452
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature25003