Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leuke...
Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia
About this item
Full title
Author / Creator
Nadeu, F , Clot, G , Delgado, J , Martín-García, D , Baumann, T , Salaverria, I , Beà, S , Pinyol, M , Jares, P , Navarro, A , Suárez-Cisneros, H , Aymerich, M , Rozman, M , Villamor, N , Colomer, D , González, M , Alcoceba, M , Terol, M J , Navarro, B , Colado, E , Payer, ÁR , Puente, X S , López-Otín, C , López-Guillermo, A , Enjuanes, A and Campo, E
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Genome studies of chronic lymphocytic leukemia (CLL) have revealed the remarkable subclonal heterogeneity of the tumors, but the clinical implications of this phenomenon are not well known. We assessed the mutational status of 28 CLL driver genes by deep-targeted next-generation sequencing and copy number alterations (CNA) in 406 previously untreat...
Alternative Titles
Full title
Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia
Authors, Artists and Contributors
Author / Creator
Clot, G
Delgado, J
Martín-García, D
Baumann, T
Salaverria, I
Beà, S
Pinyol, M
Jares, P
Navarro, A
Suárez-Cisneros, H
Aymerich, M
Rozman, M
Villamor, N
Colomer, D
González, M
Alcoceba, M
Terol, M J
Navarro, B
Colado, E
Payer, ÁR
Puente, X S
López-Otín, C
López-Guillermo, A
Enjuanes, A
Campo, E
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5843898
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5843898
Other Identifiers
ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2017.291
