A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim
A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim
About this item
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Publisher
New York: Springer US
Journal title
Language
English
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Publication information
Publisher
New York: Springer US
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Scope and Contents
Contents
Proteins are an increasingly important class of drugs used as therapeutic as well as diagnostic agents. A generic physiologically based pharmacokinetic (PBPK) model was developed in order to represent at whole body level the fundamental mechanisms driving the distribution and clearance of large molecules like therapeutic proteins. The model was bui...
Alternative Titles
Full title
A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5845054
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5845054
Other Identifiers
ISSN
1567-567X
E-ISSN
1573-8744
DOI
10.1007/s10928-017-9559-4
