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ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasi...

ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5847866

ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis

About this item

Full title

ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis

Publisher

England: John Wiley & Sons, Inc

Journal title

Aging cell, 2018-04, Vol.17 (2), p.n/a

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Summary
PINK1 (PTEN‐induced putative kinase 1) is a key regulator of mitochondrial homeostasis that is relatively depleted in aging lungs and in lung epithelial cells from patients with idiopathic pulmonary fibrosis (IPF), a disease linked with aging. Impaired PINK1 expression and accumulation of damaged mitochondria in lung epithelial cells fro...

Alternative Titles

Full title

ATF3 represses PINK1 gene transcription in lung epithelial cells to control mitochondrial homeostasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5847866

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5847866

Other Identifiers

ISSN

1474-9718

E-ISSN

1474-9726

DOI

10.1111/acel.12720

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