Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and G...
Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The metabotropic glutamate (mGlu) receptors are class C G protein-coupled receptors (GPCRs) that modulate synaptic activity and plasticity throughout the mammalian brain. Signal transduction is initiated by glutamate binding to the venus flytrap domains (VFT), which initiates a conformational change that is transmitted to the conserved heptahelical...
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Full title
Direct coupling of detergent purified human mGlu5 receptor to the heterotrimeric G proteins Gq and Gs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5849714
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5849714
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-22729-4
