Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4–NKX2-5 Interaction
Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4–NKX2-5 Interaction
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Transcription factors are fundamental regulators of gene transcription, and many diseases, such as heart diseases, are associated with deregulation of transcriptional networks. In the adult heart, zinc-finger transcription factor GATA4 is a critical regulator of cardiac repair and remodelling. Previous studies also suggest that NKX2-5 plays functio...
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Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4–NKX2-5 Interaction
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5854571
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5854571
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-22830-8
