Orchestrated control of filaggrin–actin scaffolds underpins cornification
Orchestrated control of filaggrin–actin scaffolds underpins cornification
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Epidermal stratification critically depends on keratinocyte differentiation and programmed death by cornification, leading to formation of a protective skin barrier. Cornification is dynamically controlled by the protein filaggrin, rapidly released from keratohyalin granules (KHGs). However, the mechanisms of cornification largely remain elusive, p...
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Full title
Orchestrated control of filaggrin–actin scaffolds underpins cornification
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5854575
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5854575
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ISSN
2041-4889
E-ISSN
2041-4889
DOI
10.1038/s41419-018-0407-2
