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Autophagy maintains stem cells and intestinal homeostasis in Drosophila

Autophagy maintains stem cells and intestinal homeostasis in Drosophila

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5854693

Autophagy maintains stem cells and intestinal homeostasis in Drosophila

About this item

Full title

Autophagy maintains stem cells and intestinal homeostasis in Drosophila

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-03, Vol.8 (1), p.4644-9, Article 4644

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Intestinal homeostasis is maintained by tightly controlled proliferation and differentiation of tissue-resident multipotent stem cells during aging and regeneration, which ensures organismal adaptation. Here we show that autophagy is required in Drosophila intestinal stem cells to sustain proliferation, and preserves the stem cell pool. Autophagy-d...

Alternative Titles

Full title

Autophagy maintains stem cells and intestinal homeostasis in Drosophila

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5854693

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5854693

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-23065-3

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