D₄ dopamine receptor high-resolution structures enable the discovery of selective agonists
D₄ dopamine receptor high-resolution structures enable the discovery of selective agonists
About this item
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Author / Creator
Publisher
Washington: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
Dopamine receptors are implicated in the pathogenesis and treatment of nearly every neuropsychiatric disorder. Although thousands of drugs interact with these receptors, our molecular understanding of dopaminergic drug selectivity and design remains clouded. To illuminate dopamine receptor structure, function, and ligand recognition, we determined...
Alternative Titles
Full title
D₄ dopamine receptor high-resolution structures enable the discovery of selective agonists
Authors, Artists and Contributors
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5856174
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5856174
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.aan5468
