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Antibody-dependent enhancement of severe dengue disease in humans

Antibody-dependent enhancement of severe dengue disease in humans

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5858873

Antibody-dependent enhancement of severe dengue disease in humans

About this item

Full title

Antibody-dependent enhancement of severe dengue disease in humans

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2017-11, Vol.358 (6365), p.929-932

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

For dengue viruses 1 to 4 (DENV1-4), a specific range of antibody titer has been shown to enhance viral replication in vitro and severe disease in animal models. Although suspected, such antibody-dependent enhancement of severe disease has not been shown to occur in humans. Using multiple statistical approaches to study a long-term pediatric cohort...

Alternative Titles

Full title

Antibody-dependent enhancement of severe dengue disease in humans

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5858873

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5858873

Other Identifiers

ISSN

0036-8075,1095-9203

E-ISSN

1095-9203

DOI

10.1126/science.aan6836

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