Complement C1q stimulates the progression of hepatocellular tumor through the activation of discoidi...
Complement C1q stimulates the progression of hepatocellular tumor through the activation of discoidin domain receptor 1
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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C1q is known to perform several functions in addition to the role it plays in complement activation. C1q contains a collagen-like portion and DDR1 (discoidin domain receptor 1) is a well-known collagen receptor. Accordingly, we hypothesized C1q might be a novel ligand of DDR1. This study shows for the first time C1q directly induces the activation...
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Complement C1q stimulates the progression of hepatocellular tumor through the activation of discoidin domain receptor 1
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5861131
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5861131
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-23240-6