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Complement C1q stimulates the progression of hepatocellular tumor through the activation of discoidi...

Complement C1q stimulates the progression of hepatocellular tumor through the activation of discoidi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5861131

Complement C1q stimulates the progression of hepatocellular tumor through the activation of discoidin domain receptor 1

About this item

Full title

Complement C1q stimulates the progression of hepatocellular tumor through the activation of discoidin domain receptor 1

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2018-03, Vol.8 (1), p.4908-11, Article 4908

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

C1q is known to perform several functions in addition to the role it plays in complement activation. C1q contains a collagen-like portion and DDR1 (discoidin domain receptor 1) is a well-known collagen receptor. Accordingly, we hypothesized C1q might be a novel ligand of DDR1. This study shows for the first time C1q directly induces the activation...

Alternative Titles

Full title

Complement C1q stimulates the progression of hepatocellular tumor through the activation of discoidin domain receptor 1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5861131

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5861131

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/s41598-018-23240-6

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