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Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formati...

Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formati...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5868578

Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells

About this item

Full title

Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells

Publisher

New Zealand: Dove Medical Press Limited

Journal title

OncoTargets and therapy, 2018-01, Vol.11, p.1601-1616

Language

English

Formats

Publication information

Publisher

New Zealand: Dove Medical Press Limited

More information

Scope and Contents

Contents

Hepatocellular carcinoma (HCC) has an increasing incidence and high mortality. Surgical operation is not a comprehensive strategy for liver cancer. Moreover, tolerating systemic chemotherapy is difficult for patients with HCC because hepatic function is often impaired due to underlying cirrhosis. Therefore, a comprehensive strategy for cancer treat...

Alternative Titles

Full title

Targeting DTL induces cell cycle arrest and senescence and suppresses cell growth and colony formation through TPX2 inhibition in human hepatocellular carcinoma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5868578

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5868578

Other Identifiers

ISSN

1178-6930

E-ISSN

1178-6930

DOI

10.2147/OTT.S147453

How to access this item