Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells
Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells
About this item
Full title
Author / Creator
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
Journal title
Language
English
Formats
Publication information
Publisher
Cairo, Egypt: Hindawi Publishing Corporation
Subjects
More information
Scope and Contents
Contents
Hemolytic or hemorrhagic episodes are often associated with inflammation even when infectious agents are absent suggesting that red blood cells (RBCs) release damage-associated molecular patterns (DAMPs). DAMPs activate immune and nonimmune cells through pattern recognition receptors. Heme, released from RBCs, is a DAMP and induces IL-1β production...
Alternative Titles
Full title
Induction of NLRP3 Inflammasome Activation by Heme in Human Endothelial Cells
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5883980
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5883980
Other Identifiers
ISSN
1942-0900
E-ISSN
1942-0994
DOI
10.1155/2018/4310816
