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Roles of protein kinase R in cancer: Potential as a therapeutic target

Roles of protein kinase R in cancer: Potential as a therapeutic target

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5891186

Roles of protein kinase R in cancer: Potential as a therapeutic target

About this item

Full title

Roles of protein kinase R in cancer: Potential as a therapeutic target

Publisher

England: John Wiley & Sons, Inc

Journal title

Cancer science, 2018-04, Vol.109 (4), p.919-925

Language

English

Formats

Publication information

Publisher

England: John Wiley & Sons, Inc

More information

Scope and Contents

Contents

Double‐stranded (ds) RNA‐dependent protein kinase (PKR) is a ubiquitously expressed serine/threonine protein kinase. It was initially identified as an innate immune antiviral protein induced by interferon (IFN) and activated by dsRNA. PKR is recognized as a key executor of antiviral host defense. Moreover, it contributes to inflammation and immune...

Alternative Titles

Full title

Roles of protein kinase R in cancer: Potential as a therapeutic target

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5891186

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5891186

Other Identifiers

ISSN

1347-9032

E-ISSN

1349-7006

DOI

10.1111/cas.13551

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