Live Respiratory Syncytial Virus (RSV) Vaccine Candidate Containing Stabilized Temperature-Sensitivi...
Live Respiratory Syncytial Virus (RSV) Vaccine Candidate Containing Stabilized Temperature-Sensitivity Mutations Is Highly Attenuated in RSV-Seronegative Infants and Children
About this item
Full title
Author / Creator
International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1114 Study Team , Buchholz, Ursula J , Cunningham, Coleen K , Muresan, Petronella , Gnanashanmugam, Devasena , Sato, Paul , Siberry, George K , Rexroad, Vivian , Valentine, Megan , Perlowski, Charlotte , Schappell, Elizabeth , Thumar, Bhagvinji , Luongo, Cindy , Barr, Emily , Aziz, Mariam , Yogev, Ram , Spector, Stephen A , Collins, Peter L , McFarland, Elizabeth J and Karron, Ruth A
Publisher
US: Oxford University Press
Journal title
Language
English
Formats
Publication information
Publisher
US: Oxford University Press
Subjects
More information
Scope and Contents
Contents
Abstract
Background
Respiratory syncytial virus (RSV) is the most important viral cause of severe respiratory illness in young children and lacks a vaccine. RSV cold-passage/stabilized 2 (RSVcps2) is a modification of a previously evaluated vaccine candidate in which 2 major attenuating mutations have been stabilized against deattenuation.
Alternative Titles
Full title
Live Respiratory Syncytial Virus (RSV) Vaccine Candidate Containing Stabilized Temperature-Sensitivity Mutations Is Highly Attenuated in RSV-Seronegative Infants and Children
Authors, Artists and Contributors
Author / Creator
Buchholz, Ursula J
Cunningham, Coleen K
Muresan, Petronella
Gnanashanmugam, Devasena
Sato, Paul
Siberry, George K
Rexroad, Vivian
Valentine, Megan
Perlowski, Charlotte
Schappell, Elizabeth
Thumar, Bhagvinji
Luongo, Cindy
Barr, Emily
Aziz, Mariam
Yogev, Ram
Spector, Stephen A
Collins, Peter L
McFarland, Elizabeth J
Karron, Ruth A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5894088
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5894088
Other Identifiers
ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1093/infdis/jiy066
