Krüppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of...
Krüppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes
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Author / Creator
Zhang, Tianlei , Song, Wei , Li, Zheng , Qian, Wenliang , Wei, Ling , Yang, Yan , Wang, Weina , Zhou, Xuan , Meng, Meng , Peng, Jian , Xia, Qingyou , Perrimon, Norbert and Cheng, Daojun
Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publication information
Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
In insects, juvenile hormone (JH) and the steroid hormone ecdysone have opposing effects on regulation of the larval–pupal transition. Although increasing evidence suggests that JH represses ecdysone biosynthesis during larval development, the mechanism underlying this repression is not well understood. Here, we demonstrate that the expression of t...
Alternative Titles
Full title
Krüppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5899488
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5899488
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1800435115