Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of...
Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Natural killer (NK) cell-mediated tumor cell eradication could inhibit tumor initiation and progression. However, the factors that regulate NK cell-mediated cancer cell eradication remain unclear. We determined that hepatocellular carcinoma (HCC) cells exhibit transcriptional down-regulation of NK group 2D (NKG2D) ligands and are largely resistant...
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Inhibition of Enhancer of zeste homolog 2 (EZH2) induces natural killer cell-mediated eradication of hepatocellular carcinoma cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5899497
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5899497
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1802691115