Palmitoylation-dependent activation of MC1R prevents melanomagenesis
Palmitoylation-dependent activation of MC1R prevents melanomagenesis
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Author / Creator
Chen, Shuyang , Zhu, Bo , Yin, Chengqian , Liu, Wei , Han, Changpeng , Chen, Baoen , Liu, Tongzheng , Li, Xin , Chen, Xiang , Li, Chunying , Hu, Limin , Zhou, Jun , Xu, Zhi-Xiang , Gao, Xiumei , Wu, Xu , Goding, Colin R. and Cui, Rutao
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The protein modification palmitoylation increases the ability of variant forms of the melanocortin-1 receptor (MC1R) to induce pigmentation, and this is linked to reduced development of melanomas.
Induced pigmentation to prevent skin cancer
People with red hair, fair skin and poor tanning ability have a higher risk of developing melanoma. The...
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Full title
Palmitoylation-dependent activation of MC1R prevents melanomagenesis
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5902815
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5902815
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature23887
