Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte p...
Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte proliferation
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Two major phospholipase D (PLD) isozymes in mammals, PLD1 and PLD2, hydrolyze the membrane phospholipid phosphatidylcholine to choline and the lipid messenger phosphatidic acid. Although their roles in cancer cells have been well studied, their functions in tumor microenvironment have not yet been clarified. Here, we demonstrate that PLD2 in cytoto...
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Physiological function of phospholipase D2 in anti-tumor immunity: regulation of CD8+ T lymphocyte proliferation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5908902
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5908902
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-018-24512-x