Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
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Author / Creator
Delacher, Michael , Imbusch, Charles D , Weichenhan, Dieter , Breiling, Achim , Hotz-Wagenblatt, Agnes , Träger, Ulrike , Hofer, Ann-Cathrin , Kägebein, Danny , Wang, Qi , Frauhammer, Felix , Mallm, Jan-Philipp , Bauer, Katharina , Herrmann, Carl , Lang, Philipp A , Brors, Benedikt , Plass, Christoph and Feuerer, Markus
Publisher
New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Contents
Specialized populations of regulatory T cells inhabit tissues and maintain homeostasis, and assist with repair functions there. Feuerer and colleagues identify a genome-wide DNA-methylation landscape to define this specialized subset of cells.
Regulatory T cells (T
reg
cells) perform two distinct functions: they maintain self-tolerance, an...
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Full title
Genome-wide DNA-methylation landscape defines specialization of regulatory T cells in tissues
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5912503
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5912503
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ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3799