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Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy

Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5948955

Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy

About this item

Full title

Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2018-05, Vol.115 (19), p.4927-4932

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

In the present work, we investigated the role of natural killer (NK) cells in combination therapy with oncolytic virus (OV) and bortezomib, a proteasome inhibitor. NK cells display rapid and potent immunity to metastatic and hematological cancers, and they overcome immunosuppressive effects of tumor microenvironment. We developed a mathematical mod...

Alternative Titles

Full title

Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5948955

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5948955

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1715295115

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