Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy
Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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In the present work, we investigated the role of natural killer (NK) cells in combination therapy with oncolytic virus (OV) and bortezomib, a proteasome inhibitor. NK cells display rapid and potent immunity to metastatic and hematological cancers, and they overcome immunosuppressive effects of tumor microenvironment. We developed a mathematical mod...
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Complex role of NK cells in regulation of oncolytic virus–bortezomib therapy
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5948955
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5948955
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1715295115